RPS3 antibody

Synonyms:40S ribosomal protein S3 antibody, ribosomal protein S3 antibody, RPS3 antibody
Catalogue No.:FNab07477Reactivity:Human, Mouse, Rat
Host:MouseTested Application:ELISA, WB, IHC, IF, IP
Clonality:monoclonalIsotype:IgG1
  • SPECIFICATIONS
Product Name
RPS3 antibody
Catalogue No.
FNab07477
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG1
Clone ID
5C7
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ribosomal protein S3
Alternative Names
40S ribosomal protein S3 antibody, ribosomal protein S3 antibody, RPS3 antibody
UniProt ID
P23396
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:10000-1:50000; IP: 1:1000-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Validated Images
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab07477(RPS3 Antibody) at dilution of 1:8000
IP Result of anti-RPS3 (IP:FNab07477, 3ug; Detection:FNab07477 1:600) with mouse testis tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab07477(RPS3 Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Background
40S ribosomal protein S3 (RPS3), also named as SW-cl.26, is a 243 amino acid protein,which contains one KH type-2 domain and belongs to the ribosomal protein S3P family. RPS3 localizes in the cytoplasm. RPS3 is identified in a IGF2BP1-dependent mRNP granule complex, which contains untranslated mRNAs. RPS3 plays a role in repairing various DNA damage acting as a repair UV endonuclease. Nuclear accumulation of RPS3 results in an increase in DNA repair activity to some extent, thereby sustaining neuronal survival. The calculated molecular weight of RPS3 is 26 kDa, but the modified RPS3 is about 33 kDa.