HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07404(RPGRIP1L antibody) at dilution of 1:800
IP Result of anti-RPGRIP1L (IP:FNab07404, 4ug; Detection:FNab07404 1:700) with HEK-293 cells lysate 3200ug.
Immunohistochemistry of paraffin-embedded human pancreas using FNab07404(RPGRIP1L antibody) at dilution of 1:50
Background
Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor(TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis(By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4(By similarity). Does not seem to be strictly required for ciliogenesis(By similarity).