ROBO3 antibody

Catalogue No.:FNab07373Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ROBO3 antibody
Catalogue No.
FNab07373
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
roundabout, axon guidance receptor, homolog 3(Drosophila)
UniProt ID
Q96MS0
Observed MW
55 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse stomach tissue were subjected to SDS PAGE followed by western blot with FNab07373(ROBO3 antibody) at dilution of 1:200
Immunohistochemistry of paraffin-embedded human gliomas using FNab07373(ROBO3 antibody) at dilution of 1:50
Background
Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1(By similarity). Required for hindbrain axon midline crossing.