Products
RNF7 antibody
- Product Name
- RNF7 antibody
- Catalogue No.
- FNab07361
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ring finger protein 7
- Alternative Names
- RBX2 antibody, ROC2 antibody, SAG antibody
- UniProt ID
- Q9UBF6
- Observed MW
- 13 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
human liver tissue were subjected to SDS PAGE followed by western blot with FNab07361(RNF7 antibody) at dilution of 1:500
- Background
- Probable component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
