Products
RNF213 antibody
- Product Name
- RNF213 antibody
- Catalogue No.
- FNab07351
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ring finger protein 213
- Alternative Names
- ALO17 antibody, antibody
- UniProt ID
- Q63HN8
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human spleen using FNab07351(RNF213 antibody) at dilution of 1:50
- Background
- E3 ubiquitin-protein ligase involved in angiogenesis(PubMed:21799892, PubMed:26278786, PubMed:26766444, PubMed:26126547). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression(PubMed:26766444). Also has ATPase activity(PubMed:24658080, PubMed:26126547).
