Products
RNASEH1 antibody
- Product Name
- RNASEH1 antibody
- Catalogue No.
- FNab07327
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ribonuclease H1
- Alternative Names
- RNH1 antibody
- UniProt ID
- O60930
- Observed MW
- 32 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:2000
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab07327(RNASEH1 antibody) at dilution of 1:500
IP Result of anti-RNASEH1 (IP:FNab07327, 3ug; Detection:FNab07327 1:500) with HeLa cells lysate 1200ug.
- Background
- Endonuclease that specifically degrades the RNA of RNA-DNA hybrids(PubMed:10497183). Plays a role in RNA polymerase II(RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II(PubMed:21700224).
