Products
RhoGDI antibody
- Product Name
- RhoGDI antibody
- Catalogue No.
- FNab07286
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Rho GDP dissociation inhibitor(GDI) alpha
- Alternative Names
- AGDI antibody, ARHGDIA antibody, GDIA1 antibody, Rho GDI 1 antibody, Rho GDI alpha antibody, RHOGDI antibody, RHOGDI 1 antibody
- UniProt ID
- P52565
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:5000; IHC: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07286(ARHGDIA,aGDI antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab07286(ARHGDIA,aGDI antibody) at dilution of 1:50
- Background
- Aplysia Ras-related homologs(ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange(GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA(also called Rho GDP-dissociation inhibitor 1, Rho GDI1). Rho GDI1 acts as a metastasis-related protein in colon and prostate cancer patients and may be useful as a diagnostic biomarker to prevent colon and prostate cancer metastasis.
