Products
RBPMS antibody
- Product Name
- RBPMS antibody
- Catalogue No.
- FNab07198
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RNA binding protein with multiple splicing
- Alternative Names
- HERMES antibody
- UniProt ID
- Q93062
- Observed MW
- 28-30 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, FC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab07198(RBPMS antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07198(RBPMS antibody) at dilution of 1:50
- Background
- Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).
