Products
RBPJ antibody
- Product Name
- RBPJ antibody
- Catalogue No.
- FNab07195
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- recombination signal binding protein for immunoglobulin kappa J region
- Alternative Names
- IGKJRB antibody, IGKJRB1 antibody, RBPJK antibody, RBPSUH antibody
- UniProt ID
- Q06330
- Observed MW
- 55 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
Validated Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with FNab07195(RBPJ antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab07195(RBPJ antibody) at dilution of 1:100
- Background
- The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
