RBM15 antibody

Synonyms:FLJ12479 antibody, FLJ21943 antibody, One twenty two protein 1 antibody, OTT antibody, OTT1 antibody, RBM15 antibody, RNA binding motif protein 15 antibody, SPEN antibody
Catalogue No.:FNab07162Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
RBM15 antibody
Catalogue No.
FNab07162
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
RNA binding motif protein 15
Alternative Names
FLJ12479 antibody, FLJ21943 antibody, One twenty two protein 1 antibody, OTT antibody, OTT1 antibody, RBM15 antibody, RNA binding motif protein 15 antibody, SPEN antibody
UniProt ID
Q96T37
Observed MW
100-107 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07162(RBM15 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab07162(RBM15 antibody) at dilution of 1:100
Background
May function as an mRNA export factor, stimulating export and expression of RTE-containing mRNAs which are present in many retrotransposons that require to be exported prior to splicing. High affinity binding of pre-mRNA to RBM15 may allow targeting of the mRNP to the export helicase DBP5 in a manner that is independent of splicing-mediated NXF1 deposition, resulting in export prior to splicing. May be implicated in HOX gene regulation.