Products
RBM14 antibody
- Product Name
- RBM14 antibody
- Catalogue No.
- FNab07161
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RNA binding motif protein 14
- Alternative Names
- SIP antibody
- UniProt ID
- Q96PK6
- Observed MW
- 70-75 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07161(RBM14 antibody) at dilution of 1:800
- Background
- Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).
