RANBP10 antibody

Synonyms:KIAA1464 antibody
Catalogue No.:FNab07101Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
RANBP10 antibody
Catalogue No.
FNab07101
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
RAN binding protein 10
Alternative Names
KIAA1464 antibody
UniProt ID
Q6VN20
Observed MW
67-70 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07101(RANBP10 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human hepatocirrhosis using FNab07101(RANBP10 antibody) at dilution of 1:50
Background
Acts as a guanine nucleotide exchange factor(GEF) for RAN GTPase(By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function(By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway.