Products
RAN antibody
- Product Name
- RAN antibody
- Catalogue No.
- FNab07100
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RAN, member RAS oncogene family
- Alternative Names
- ARA24 antibody
- UniProt ID
- P62826
- Observed MW
- 24 kDa
Application
- Tested Applications
- ELISA, IHC, IF, IP, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07100(RAN Antibody) at dilution of 1:1000
IP Result of anti-RAN (IP:FNab07100, 4ug; Detection:FNab07100 1:1000) with mouse kidney tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab07100(RAN Antibody) at dilution of 1:50
- Background
- GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle(By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
