anti- RAD51 antibody
FNab07079
Catalogue No.
- Synonyms:
- RAD51A, RECA
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IP,IHC
Product Information
- Product Name
- anti- RAD51 antibody
- Catalogue No.
- FNab07079
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
- Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Immunogen Information
- Immunogen
- RAD51 homolog
- Synonyms
- RAD51A, RECA
- Observed MW
- 37 kDa
Application
- Tested Application
- ELISA, WB, IP,IHC
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500
Uniprot information
- UniProt ID
- Q06609
Images
- Image 1
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Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab07079(RAD51 Antibody) at dilution of 1:200
- Image 3
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IP Result of anti-RAD51 (IP:FNab07079, 3ug; Detection:FNab07079 1:1000) with mouse testis tissue lysate 4000ug.
- Image 4
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab07079(RAD51 Antibody) at dilution of 1:1000