Products
RAD51 antibody
Category:
Research Area:
- SPECIFICATIONS
- Product Name
- RAD51 antibody
- Catalogue No.
- FNab07079
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RAD51 homolog
- Alternative Names
- DNA repair protein RAD51 homolog 1 (HsRAD51 antibody, hRAD51)|RAD51 homolog A|RAD51|RAD51A|RECA antibody
- UniProt ID
- Q06609
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, WB, IP,IHC
- Recommended dilution
- WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500
Validated Images
![](https://www.fn-test.com/content/uploads/product/images/antibody4/FNab07079.jpg)
![](https://www.fn-test.com/content/uploads/product/images/antibody3/FNab07079.jpg)
![](https://www.fn-test.com/content/uploads/product/images/antibody1/FNab07079.jpg)
- Background
- Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.