HeLa cells were subjected to SDS PAGE followed by western blot with FNab07053(RABEP1 antibody) at dilution of 1:400
IP Result of anti-RABEP1 (IP:FNab07053, 3ug; Detection:FNab07053 1:500) with HeLa cells lysate 3800ug.
Background
Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane(PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.