fetal human brain tissue were subjected to SDS PAGE followed by western blot with FNab07037(RAB4A Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human heart tissue slide using FNab07037(RAB4A Antibody) at dilution of 1:200
Immunofluorescent analysis of ( -20℃ Ethanol ) fixed NIH/3T3 cells using FNab07037 ( RAB4A Antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Background
The human RAB genes share structural and biochemical properties with the Ras gene superfamily, and RAB4(synonym: RAB4A) is a small GTPase belonging to this Ras superfamily. Accumulating data suggests an important role for RAB proteins either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from endoplasmic reticulum to the Golgi complex and to secretory vesicles involves the movement of carrier vesicles, a process that appears to involve RAB protein function. RAB4 may also function as regulator along the receptor recycling pathway.