Products
RAB35 antibody
- Product Name
- RAB35 antibody
- Catalogue No.
- FNab07019
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RAB35, member RAS oncogene family
- Alternative Names
- RAB1C antibody, RAY antibody
- UniProt ID
- Q15286
- Observed MW
- 25 kDa
Application
- Tested Applications
- ELISA, WB, IP, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human brain tissue were subjected to SDS PAGE followed by western blot with FNab07019(RAB35 antibody) at dilution of 1:600
IP result of anti-RAB35(IP:FNab07019, 4ug; Detection:FNab07019 1:600) with mouse brain tissue lysate 2400 ug
Immunohistochemistry of paraffin-embedded human brain tissue slide using FNab07019(RAB35 Antibody) at dilution of 1:50
- Background
- The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate(PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth.
