BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab07004(RAB22A antibody) at dilution of 1:400
IP result of anti-RAB22A(IP:FNab07004, 4ug; Detection:FNab07004 1:300) with COLO 320 cells lysate 2560 ug
Immunohistochemistry of paraffin-embedded human gliomas using FNab07004(RAB22A antibody) at dilution of 1:50
Background
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.