Products
RAB12 antibody
- Product Name
- RAB12 antibody
- Catalogue No.
- FNab06995
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- RAB12, member RAS oncogene family
- Alternative Names
- RAB12 antibody, Ras related protein Rab 12 antibody
- UniProt ID
- Q6IQ22
- Observed MW
- 28 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP, IF
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:50-1:500
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06995(RAB12 antibody) at dilution of 1:500
IP Result of anti-RAB12 (IP:FNab06995, 4ug; Detection:FNab06995 1:500) with HeLa cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human liver using FNab06995(RAB12 antibody) at dilution of 1:100
Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using FNab06995 (RAB12 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy(By similarity).
