HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06973(PYGB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver cancer using FNab06973(PYGB antibody) at dilution of 1:100
Background
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.