A549 cells were subjected to SDS PAGE followed by western blot with FNab06950(PTRF antibody) at dilution of 1:1000
IP Result of anti-PTRF (IP:FNab06950, 3ug; Detection:FNab06950 1:800) with mouse lung tissue lysate 5160ug.
Immunohistochemistry of paraffin-embedded human pancreas using FNab06950(PTRF antibody) at dilution of 1:100
Background
Plays an important role in caveolae formation and organization. Required for the sequestration of mobile caveolin into immobile caveolae. Termination of transcription by RNA polymerase I involves pausing of transcription by TTF1, and the dissociation of the transcription complex, releasing pre-rRNA and RNA polymerase I from the template. PTRF is required for dissociation of the ternary transcription complex.