Products
PTPN14 antibody
- Product Name
- PTPN14 antibody
- Catalogue No.
- FNab06933
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein tyrosine phosphatase, non-receptor type 14
- Alternative Names
- PEZ antibody, PTPD2 antibody
- UniProt ID
- Q15678
- Observed MW
- 150 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
K-562 cells were subjected to SDS PAGE followed by western blot with FNab06933(PTPN14 antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human placenta using FNab06933(PTPN14 antibody) at dilution of 1:50
- Background
- Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.
