Products

anti- PTPMT1 antibody

FNab06931 Catalogue No.
Synonyms
MOSP, PLIP
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- PTPMT1 antibody
Catalogue No.
FNab06931
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity).
Immunogen Information
Immunogen
protein tyrosine phosphatase, mitochondrial 1
Synonyms
MOSP, PLIP
Observed MW
21-23 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:1000; IHC: 1:20-1:200
Uniprot information
UniProt ID
Q8WUK0
Images
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06931(PTPMT1 antibody) at dilution of 1:50
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab06931(PTPMT1 antibody) at dilution of 1:300