Products
PTPMT1 antibody
- Product Name
- PTPMT1 antibody
- Catalogue No.
- FNab06931
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein tyrosine phosphatase, mitochondrial 1
- Alternative Names
- MOSP antibody, PLIP antibody
- UniProt ID
- Q8WUK0
- Observed MW
- 21-23 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab06931(PTPMT1 antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06931(PTPMT1 antibody) at dilution of 1:50
- Background
- Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity).
