HeLa cells were subjected to SDS PAGE followed by western blot with FNab06919(PTGR1 antibody) at dilution of 1:3000
IP Result of anti-PTGR1 (IP:FNab06919, 4ug; Detection:FNab06919 1:500) with HepG2 cells lysate 3200ug.
Background
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha(By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.