Products

PTGES3 antibody

Synonyms:P23 antibody, TEBP antibody
Catalogue No.:FNab06918Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IF, IP, WB, FC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PTGES3 antibody
Catalogue No.
FNab06918
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
prostaglandin E synthase 3(cytosolic)
Alternative Names
P23 antibody, TEBP antibody
UniProt ID
Q15185
Observed MW
21-23 kDa
Application
Tested Applications
ELISA, IF, IP, WB, FC
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200
Validated Images
rat brain tissue were subjected to SDS PAGE followed by western blot with FNab06918( PTGES3 Antibody) at dilution of 1:1000
IP Result of anti-PTGES3 (IP:FNab06918, 3ug; Detection:FNab06918 1:300) with mouse heart tissue lysate 4000ug.
Background
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2(PGH2) to prostaglandin E2(PGE2)(PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes(PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway(PubMed:24711448).