PSMB4 antibody

Synonyms:PROS26 antibody
Catalogue No.:FNab06873Reactivity:Human
Host:RabbitTested Application:ELISA, IHC, IF, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PSMB4 antibody
Catalogue No.
FNab06873
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
proteasome(prosome, macropain) subunit, beta type, 4
Alternative Names
PROS26 antibody
UniProt ID
P28070
Observed MW
25 kDa
Application
Tested Applications
ELISA, IHC, IF, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06873(PSMB4 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06873(PSMB4 antibody) at dilution of 1:50
Background
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal macrophage proteasome(By similarity). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.