P-selectin antibody

Synonyms:CD62 antibody, CD62P antibody, FLJ45155 antibody, GMP 140 antibody, GMP140 antibody, GMRP antibody, Granule membrane protein 140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, P-selectin antibody, SELP antibody
Catalogue No.:FNab06851Reactivity:Human
Host:RabbitTested Application:ELISA, IHC, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
P-selectin antibody
Catalogue No.
FNab06851
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
selectin P(granule membrane protein 140kDa, antigen CD62)
Alternative Names
CD62 antibody, CD62P antibody, FLJ45155 antibody, GMP 140 antibody, GMP140 antibody, GMRP antibody, Granule membrane protein 140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, P-selectin antibody, SELP antibody
UniProt ID
P16109
Observed MW
100 kDa,150 kD
Application
Tested Applications
ELISA, IHC, WB
Recommended dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06851(P-selectin Antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human lung cancer using FNab06851(SELP antibody) at dilution of 1:50
Background
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.