Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06851(P-selectin Antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human lung cancer using FNab06851(SELP antibody) at dilution of 1:50
Background
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.