A549 cells were subjected to SDS PAGE followed by western blot with FNab06746( PRAME Antibody) at dilution of 1:300
IP Result of anti-PRAME (IP:FNab06746, 3ug; Detection:FNab06746 1:300) with A549 cells lysate 2400ug.
Background
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.