Products

PPP2R2B antibody

Synonyms:PP2A subunit B isoform beta antibody, PP2A subunit B isoform R2 beta antibody, PP2AB BETA antibody, PP2APR55 BETA antibody, PPP2R2B antibody, PR2AB BETA antibody, PR2AB55 BETA antibody, PR2APR55 BETA antibody, PR52B antibody, PR55 BETA antibody, SCA12 antibody
Catalogue No.:FNab06717Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PPP2R2B antibody
Catalogue No.
FNab06717
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
protein phosphatase 2(formerly 2A), regulatory subunit B, beta isoform
Alternative Names
PP2A subunit B isoform beta antibody, PP2A subunit B isoform R2 beta antibody, PP2AB BETA antibody, PP2APR55 BETA antibody, PPP2R2B antibody, PR2AB BETA antibody, PR2AB55 BETA antibody, PR2APR55 BETA antibody, PR52B antibody, PR55 BETA antibody, SCA12 antibody
UniProt ID
Q00005
Observed MW
52 kDa
Application
Tested Applications
ELISA, WB, IF, IP
Recommended dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IF: 1:10-1:100
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06717(PPP2R2B antibody) at dilution of 1:500
IP Result of PPP2R2B antibody (IP: FNab06717, 4ug; Detection: FNab06717 1:500) with SH-SY5Y cells lysate 2000ug.
Immunofluorescent analysis of HeLa cells using FNab06717 (PPP2R2B antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
Background
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).