Products

PPP1R8 antibody

Synonyms:ARD1 antibody, NIPP1 antibody
Catalogue No.:FNab06709Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, IHC, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PPP1R8 antibody
Catalogue No.
FNab06709
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
protein phosphatase 1, regulatory (inhibitor) subunit 8
Alternative Names
ARD1 antibody, NIPP1 antibody
UniProt ID
Q12972
Observed MW
40 kDa
Application
Tested Applications
ELISA, IHC, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab06709(PPP1R8 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer using FNab06709(PPP1R8 antibody) at dilution of 1:100
Background
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.