human heart tissue were subjected to SDS PAGE followed by western blot with FNab06701(PPP1R13L antibody) at dilution of 1:200
IP Result of anti-iASPP (IP:FNab06701, 4ug; Detection:FNab06701 1:1000) with PC-3 cells lysate 1040ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06701(PPP1R13L antibody) at dilution of 1:50
Background
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.