PPP1R13L antibody

Synonyms:IASPP antibody, NKIP1 antibody, PPP1R13BL antibody, RAI antibody
Catalogue No.:FNab06701Reactivity:Human, Rat, Mouse
Host:RabbitTested Application:ELISA, IHC, IF, IP, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PPP1R13L antibody
Catalogue No.
FNab06701
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
protein phosphatase 1, regulatory(inhibitor) subunit 13 like
Alternative Names
IASPP antibody, NKIP1 antibody, PPP1R13BL antibody, RAI antibody
UniProt ID
Q8WUF5
Observed MW
110 kDa
Application
Tested Applications
ELISA, IHC, IF, IP, WB
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
human heart tissue were subjected to SDS PAGE followed by western blot with FNab06701(PPP1R13L antibody) at dilution of 1:200
IP Result of anti-iASPP (IP:FNab06701, 4ug; Detection:FNab06701 1:1000) with PC-3 cells lysate 1040ug.
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06701(PPP1R13L antibody) at dilution of 1:50
Background
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.