SW480 cells were subjected to SDS PAGE followed by western blot with FNab06694(PPP1CB antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab06694(PPP1CB antibody) at dilution of 1:100
Background
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.