Products
PPM1B antibody
- Product Name
- PPM1B antibody
- Catalogue No.
- FNab06685
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein phosphatase 1B(formerly 2C), magnesium-dependent, beta isoform
- Alternative Names
- PP2CB antibody
- UniProt ID
- O75688
- Observed MW
- 50-53 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06685(PPM1B antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06685(PPM1B Antibody) at dilution of 1:200
- Background
- Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
