Products
PPARGC1B antibody
- Product Name
- PPARGC1B antibody
- Catalogue No.
- FNab06666
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- peroxisome proliferator-activated receptor gamma, coactivator 1 beta
- Alternative Names
- PERC antibody, PGC1 antibody, PGC1B antibody, PPARGC1 antibody
- UniProt ID
- Q86YN6
- Observed MW
- 100-110 kDa
Application
- Tested Applications
- ELISA, IP, WB
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab06666( PPARGC1B Antibody) at dilution of 1:300
IP Result of anti-PPARGC1B (IP:FNab06666, 4ug; Detection:FNab06666 1:300) with mouse liver tissue lysate 4000ug.
- Background
- Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1(NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
