human kidney tissue were subjected to SDS PAGE followed by western blot with FNab06621(POLR2C antibody) at dilution of 1:500
IP Result of anti-POLR2C (IP:FNab06621, 4ug; Detection:FNab06621 1:500) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab06621(POLR2C antibody) at dilution of 1:100
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft(By similarity).