POLR2C antibody

Catalogue No.:FNab06621Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
POLR2C antibody
Catalogue No.
FNab06621
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
polymerase(RNA) II(DNA directed) polypeptide C, 33kDa
UniProt ID
P19387
Observed MW
33 kDa
Application
Tested Applications
ELISA, WB, IHC, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
human kidney tissue were subjected to SDS PAGE followed by western blot with FNab06621(POLR2C antibody) at dilution of 1:500
IP Result of anti-POLR2C (IP:FNab06621, 4ug; Detection:FNab06621 1:500) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human cervical cancer using FNab06621(POLR2C antibody) at dilution of 1:100
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft(By similarity).