Products
Plexin B2 antibody
- Product Name
- Plexin B2 antibody
- Catalogue No.
- FNab06545
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- plexin B2
- Alternative Names
- KIAA0315 antibody, MM1 antibody, Nbla00445 antibody, PLEXB2 antibody, Plexin B2 antibody, PLXNB2 antibody
- UniProt ID
- O15031
- Observed MW
- 80 kDa, 170 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500-1:2000; IP :1:500-1:2000
Validated Images
22RV1 cells were subjected to SDS PAGE followed by western blot with FNab06545(Plexin B2 Antibody) at dilution of 1:1000
IP Result of anti-Plexin B2 (IP:FNab06545, 4ug; Detection:FNab06545 1:1000) with mouse liver tissue lysate 4000ug.
- Background
- Semaphorins, originally identified as axon guidance molecules, have also been implicated in angiogenesis, immunoregulation, and cancer (PMID: 16584533). Plexins are main receptors for semaphorins and are thought to control many of the functional effects of semaphorins. PLXNB2 is one of the three plexin-B family members which participate in axon guidance and cell migration in response to semaphorins. It has been reported that plexin B2 precursor is 240 kDa and can be cleaved into alpha subunit (~170-kDa) and beta subunit (80-kDa) (PMID: 12533544).
