Products

anti- PLEKHF1 antibody

FNab06540 Catalogue No.
Synonyms
Apoptosis inducing protein, APPD, LAPF, Phafin 1, PHAFIN1, PLEKHF1, ZFYVE15
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, WB, IF, IHC
Product Information
Product Name
anti- PLEKHF1 antibody
Catalogue No.
FNab06540
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.
Immunogen Information
Immunogen
pleckstrin homology domain containing, family F(with FYVE domain) member 1
Synonyms
Apoptosis inducing protein, APPD, LAPF, Phafin 1, PHAFIN1, PLEKHF1, ZFYVE15
Observed MW
31 kDa
Application
Tested Application
ELISA, WB, IF, IHC
Recommended dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Uniprot information
UniProt ID
Q96S99
Images
Immunohistochemistry of paraffin-embedded human brain slide using FNab06540(PLEKHF1 Antibody) at dilution of 1:50
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06540(PLEKHF1 antibody) at dilution of 1:500