Products
PLEKHF1 antibody
- Product Name
- PLEKHF1 antibody
- Catalogue No.
- FNab06540
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- pleckstrin homology domain containing, family F(with FYVE domain) member 1
- Alternative Names
- Apoptosis inducing protein antibody, APPD antibody, LAPF antibody, Phafin 1 antibody, PHAFIN1 antibody, PLEKHF1 antibody, ZFYVE15 antibody
- UniProt ID
- Q96S99
- Observed MW
- 31 kDa
Application
- Tested Applications
- ELISA, WB, IF, IHC
- Recommended dilution
- WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Validated Images
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06540(PLEKHF1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human brain slide using FNab06540(PLEKHF1 Antibody) at dilution of 1:50
- Background
- May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.
