Products
PKC iota antibody
- Product Name
- PKC iota antibody
- Catalogue No.
- FNab06486
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- protein kinase C, iota
- Alternative Names
- aPKC lambda/iota antibody, DXS1179E antibody, PKC iota antibody, PKCI antibody, PRKC lambda/iota antibody, PRKCI antibody, Protein kinase C iota type antibody, protein kinase C antibody, iota antibody
- UniProt ID
- P41743
- Observed MW
- 68 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IP
- Recommended dilution
- WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06486(PRKCI antibody) at dilution of 1:500
IP Result of anti-PKC iota (IP: FNab06486, 3ug; Detection: FNab06486 1:500) with HeLa cells lysate 2500ug.
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06486(PRKCI Antibody) at dilution of 1:200
Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using FNab06486 (PKC iota antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
- Background
- Calcium-and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis.
