Products
PI4K2B antibody
- Product Name
- PI4K2B antibody
- Catalogue No.
- FNab06425
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- phosphatidylinositol 4-kinase type 2 beta
- UniProt ID
- Q8TCG2
- Observed MW
- 50-54 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06425(PI4K2B antibody) at dilution of 1:400
Immunohistochemistry of paraffin-embedded human liver using FNab06425(PI4K2B antibody) at dilution of 1:100
- Background
- Together with PI4K2A and the type III PI4Ks(PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol(PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate(PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate(InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
