Products

anti- PER2 antibody

FNab06312 Catalogue No.
Synonyms
FASPS, hPER2, KIAA0347, PER2, period homolog 2
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, WB, IP
Product Information
Product Name
anti- PER2 antibody
Catalogue No.
FNab06312
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.
Immunogen Information
Immunogen
period homolog 2
Synonyms
FASPS, hPER2, KIAA0347, PER2, period homolog 2
Observed MW
136 kDa
Application
Tested Application
ELISA, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000
Uniprot information
UniProt ID
O15055
Images
IP Result of anti-PER2 (IP:FNab06312, 3ug; Detection:FNab06312 1:300) with HEK-293 cells lysate 1000ug.
BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab06312(PER2 antibody) at dilution of 1:600