PELO antibody

Catalogue No.:FNab06305Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PELO antibody
Catalogue No.
FNab06305
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
pelota homolog(Drosophila)
UniProt ID
Q9BRX2
Observed MW
43-45 kDa
Application
Tested Applications
ELISA, WB, IHC, IF, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
SKOV-3 cells were subjected to SDS PAGE followed by western blot with FNab06305(PELO antibody) at dilution of 1:1000
IP Result of anti-PELO (IP:FNab06305, 4ug; Detection:FNab06305 1:500) with HEK-293 cells lysate 1200ug.
Immunohistochemistry of paraffin-embedded human ovary tumor using FNab06305(PELO antibody) at dilution of 1:100
Background
Required for normal chromosome segregation during cell division and genomic stability(By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity(Potential).