PDE5A antibody

Synonyms:PDE5 antibody
Catalogue No.:FNab06256Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
PDE5A antibody
Catalogue No.
FNab06256
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
phosphodiesterase 5A, cGMP-specific
Alternative Names
PDE5 antibody
UniProt ID
O76074
Observed MW
100KD
Application
Tested Applications
ELISA, WB, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
SKOV-3 cells were subjected to SDS PAGE followed by western blot with FNab06256(PDE5A antibody) at dilution of 1:3000
Immunofluorescent analysis of SKOV-3 cells using FNab06256 (PDE5A antibody) at dilution of 1:50 and FITC-conjugated Goat Anti-Rabbit IgG(H+L).
Background
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP(PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP(PubMed:15489334).