SKOV-3 cells were subjected to SDS PAGE followed by western blot with FNab06256(PDE5A antibody) at dilution of 1:3000
Immunofluorescent analysis of SKOV-3 cells using FNab06256 (PDE5A antibody) at dilution of 1:50 and FITC-conjugated Goat Anti-Rabbit IgG(H+L).
Background
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP(PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP(PubMed:15489334).