mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06255(PED4D antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab06255(PDE4D antibody) at dilution of 1:100
Background
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3', 5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.