Products
PCSK4 antibody
- Product Name
- PCSK4 antibody
- Catalogue No.
- FNab06225
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- proprotein convertase subtilisin/kexin type 4
- Alternative Names
- PC4 antibody, PCSK4 antibody, Proprotein convertase 4 antibody, SPC5 antibody
- UniProt ID
- Q6UW60
- Observed MW
- 54kd
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
human testis tissue were subjected to SDS PAGE followed by western blot with FNab06225(PCSK4 antibody) at dilution of 1:200
- Background
- Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues(By similarity). In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida(By similarity). Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolytical processing and activation of proteins such as IGF2(PubMed:16040806). May also participate to folliculogenesis in the ovaries(By similarity).
