Products

anti- PCM1 antibody

FNab06212 Catalogue No.
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- PCM1 antibody
Catalogue No.
FNab06212
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
pericentriolar material 1
Observed MW
300 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
Q15154
Images
Immunohistochemistry of paraffin-embedded human liver cancer using FNab06212 (PCM1 Antibody) at dilution of 1:50
HeLa cells were subjected to SDS PAGE followed by western blot with FNab06212 (PCM1 antibody) at dilution of 1:1000