Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06181(PBRM1 antibody) at dilution of 1:500
IP Result of anti-PBRM1 (IP:FNab06181, 3ug; Detection:FNab06181 1:300) with HEK-293 cells lysate 1800ug.
Background
Involved in transcriptional activation and repression of select genes by chromatin remodeling(alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.