Products
PAPD5 antibody
- Product Name
- PAPD5 antibody
- Catalogue No.
- FNab06139
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- PAP associated domain containing 5
- Alternative Names
- PAPD5 antibody, Terminal uridylyltransferase 3 antibody, TRF4 2 antibody, TUTase 3 antibody
- UniProt ID
- Q8NDF8
- Observed MW
- 50 kDa, 80 kDa
Application
- Tested Applications
- ELISA, WB, IP
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab06139(PAPD5 antibody) at dilution of 1:1000
IP Result of anti-PAPD5 (IP:FNab06139, 3ug; Detection:FNab06139 1:500) with Jurkat cells lysate 1600ug.
- Background
- Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
