Products
PAIP2 antibody
- Product Name
- PAIP2 antibody
- Catalogue No.
- FNab06118
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- poly(A) binding protein interacting protein 2
- Alternative Names
- PAIP2A antibody
- UniProt ID
- Q9BPZ3
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:20-1:200
Validated Images
A431 cells were subjected to SDS PAGE followed by western blot with FNab06118(PAIP2 antibody) at dilution of 1:500
- Background
- Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
